Dammit. I was just watching something about this on Speedvision the other night. Too bad my short term memory is going away, but as I remember Indian made V-4s back in the 1920s. There may have been earlier ones too.
I don't know what bike you have in mind, but I'm fairly certain it's not going to be a Honda. Here's one from 1933...
According to Motorcycle Online:
Dollar V4, 748 cc, 22 hp @ 4000 rpm, France, 1933. Chassis constructed entirely of triangulated straight members, at the time unusual for motorcycles but common in aircraft design because of its light weight and rigidity. Devastated by World War I and the global depression of the 1930's, France promoted agricultural efforts and did not encourage the production of high-performance motorcycles. The Dollar was discontinued in 1939.