Short trips down the interstate are OK, but are usually just a means of getting somewhere to do some backroads for me. It's just too boring to take a long ride and I hate being around semis in my cage to say nothing of being on the bike. They're just no fun.
In this part of B.C. Canada we do NOT have massive interstate hwys. So when I say 5 or 8 hrs of the Mtn hwys that means basically 2-lane twisty up & down mtn roads along with some that have four lanes so those I prefer over doodling around the back roads in the lower gears & with hope I will not hit gravel all over the next bend.